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. 2008 Aug;31(8):1686–1696. doi: 10.2337/dc08-9022

Table 6.

Sensitivity analysis: 30-year cost/QALY for ranges of assumptions about selected parameters

Ref. Cost of interventions
Quality weights
Unrelated medical costs
Cost of dying
General medical costs
Discount rates
−20% +20% −20% +20% $5,000 $10,000 $20,000 $40,000 −20% +20% 0% 6%
Do everything, 100% performance $36,380 $28,203 $44,557 $37,128 $35,641 $39,196 $42,012 $34,913 $33,445 $37,281 $35,479 $31,264 $42,936
Do everything, feasible performance $42,249 $32,981 $51,516 $43,214 $41,299 $44,892 $47,536 $40,740 $39,232 $43,066 $41,431 $36,376 $49,777
Aspirin to high-risk individuals $2,779 $2,122 $3,436 $2,765 $2,794 $7,380 $11,981 $1,294 −$192 $2,881 $2,677 $2,981 $2,626
BMI <30 kg/m2 $18,941 $14,463 $23,420 $19,610 $18,305 $20,667 $22,392 $17,495 $16,048 $19,631 $18,251 $15,373 $23,625
Blood pressure <140/90 mmHg in nondiabetic individuals $52,983 $41,263 $64,702 $52,880 $53,073 $57,473 $61,964 $51,338 $49,693 $54,105 $51,860 $46,182 $61,562
CAD: LDL cholesterol <100 mg/dl $39,130 $31,670 $46,590 $36,978 $41,550 $50,274 $61,419 $37,497 $35,865 $38,764 $39,496 $35,546 $44,093
Diabetes: blood pressure <130/80 mmHg $25,317 $19,499 $31,134 $25,667 $24,933 $28,653 $31,989 $23,883 $22,450 $26,071 $24,562 $22,187 $29,406
Diabetes: A1C <7% $48,759 $37,468 $60,050 $52,590 $45,464 $46,828 $44,897 $47,183 $45,606 $50,298 $47,220 $40,331 $60,796
Diabetes: LDL cholesterol <100 mg/dl $67,199 $53,518 $80,880 $67,703 $66,602 $71,062 $74,924 $65,547 $63,894 $67,440 $66,957 $57,391 $80,119
High-risk CAD: LDL cholesterol <130 mg/dl $83,327 $66,585 $100,069 $83,053 $83,613 $87,567 $91,806 $81,481 $79,636 $83,404 $83,250 $72,157 $97,117
Low-risk CAD: LDL cholesterol <160 mg/dl $272,061 $213,877 $330,245 $279,391 $264,971 $275,202 $278,343 $269,078 $266,096 $275,833 $268,289 $171,106 $550,886
Pre-diabetes: FPG <110 mg/dl $17,478 $12,860 $22,096 $19,128 $16,054 $15,145 $12,812 $16,082 $14,685 $18,601 $16,355 $13,796 $22,585
Smoking: stop −$1,755 −$2,068 −$1,442 −$1,751 −$1,758 $2,516 $6,787 −$3,163 −$4,571 −$1,091 −$2,419 −$1,711 −$1,529