Table 6.
Sensitivity analysis: 30-year cost/QALY for ranges of assumptions about selected parameters
| Ref. | Cost of interventions
|
Quality weights
|
Unrelated medical costs
|
Cost of dying
|
General medical costs
|
Discount rates
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| −20% | +20% | −20% | +20% | $5,000 | $10,000 | $20,000 | $40,000 | −20% | +20% | 0% | 6% | ||
| Do everything, 100% performance | $36,380 | $28,203 | $44,557 | $37,128 | $35,641 | $39,196 | $42,012 | $34,913 | $33,445 | $37,281 | $35,479 | $31,264 | $42,936 |
| Do everything, feasible performance | $42,249 | $32,981 | $51,516 | $43,214 | $41,299 | $44,892 | $47,536 | $40,740 | $39,232 | $43,066 | $41,431 | $36,376 | $49,777 |
| Aspirin to high-risk individuals | $2,779 | $2,122 | $3,436 | $2,765 | $2,794 | $7,380 | $11,981 | $1,294 | −$192 | $2,881 | $2,677 | $2,981 | $2,626 |
| BMI <30 kg/m2 | $18,941 | $14,463 | $23,420 | $19,610 | $18,305 | $20,667 | $22,392 | $17,495 | $16,048 | $19,631 | $18,251 | $15,373 | $23,625 |
| Blood pressure <140/90 mmHg in nondiabetic individuals | $52,983 | $41,263 | $64,702 | $52,880 | $53,073 | $57,473 | $61,964 | $51,338 | $49,693 | $54,105 | $51,860 | $46,182 | $61,562 |
| CAD: LDL cholesterol <100 mg/dl | $39,130 | $31,670 | $46,590 | $36,978 | $41,550 | $50,274 | $61,419 | $37,497 | $35,865 | $38,764 | $39,496 | $35,546 | $44,093 |
| Diabetes: blood pressure <130/80 mmHg | $25,317 | $19,499 | $31,134 | $25,667 | $24,933 | $28,653 | $31,989 | $23,883 | $22,450 | $26,071 | $24,562 | $22,187 | $29,406 |
| Diabetes: A1C <7% | $48,759 | $37,468 | $60,050 | $52,590 | $45,464 | $46,828 | $44,897 | $47,183 | $45,606 | $50,298 | $47,220 | $40,331 | $60,796 |
| Diabetes: LDL cholesterol <100 mg/dl | $67,199 | $53,518 | $80,880 | $67,703 | $66,602 | $71,062 | $74,924 | $65,547 | $63,894 | $67,440 | $66,957 | $57,391 | $80,119 |
| High-risk CAD: LDL cholesterol <130 mg/dl | $83,327 | $66,585 | $100,069 | $83,053 | $83,613 | $87,567 | $91,806 | $81,481 | $79,636 | $83,404 | $83,250 | $72,157 | $97,117 |
| Low-risk CAD: LDL cholesterol <160 mg/dl | $272,061 | $213,877 | $330,245 | $279,391 | $264,971 | $275,202 | $278,343 | $269,078 | $266,096 | $275,833 | $268,289 | $171,106 | $550,886 |
| Pre-diabetes: FPG <110 mg/dl | $17,478 | $12,860 | $22,096 | $19,128 | $16,054 | $15,145 | $12,812 | $16,082 | $14,685 | $18,601 | $16,355 | $13,796 | $22,585 |
| Smoking: stop | −$1,755 | −$2,068 | −$1,442 | −$1,751 | −$1,758 | $2,516 | $6,787 | −$3,163 | −$4,571 | −$1,091 | −$2,419 | −$1,711 | −$1,529 |