TABLE 2.

Nucleotide and short-chain acyl-CoA content in fed db/db livers

	AMP (μmol/g)	ADP (μmol/g)	ATP (μmol/g)	CEC	Acetyl-CoA (nmol/g)	Propionyl-CoA (nmol/g)	Succinyl-CoA (nmol/g)	Malonyl-CoA (nmol/g)
Ad-shCT	1.05 ± 0.06	1.24 ± 0.08	1.02 ± 0.08	0.47 ± 0.01	140.13 ± 1.95	48.12 ± 0.84	31.44 ± 3.12	2.079 ± 0.239
Ad-shPck1	0.77 ± 0.11*	1.16 ± 0.07	1.47 ± 0.17†	0.54 ± 0.02†	130.29 ± 2.47	56.68 ± 1.25†	31.31 ± 2.10	4.472 ± 0.932*

Data are means ± SE. n = 8.

^*P < 0.05;

^†P < 0.01 vs. control virus treatment; unpaired Student's t test. Tissue was obtained 14 days after treatment. CEC = (ATP + 1/2 AMP)/(ATP + ADP + AMP).