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Immunohistochemistry on paraffin sections of 17-week-old pancreas. Images show wild-type and Sox4 heterozygous animals stained with insulin, glucagon, somatostatin, PDX1, Nkx-6.1, NeuroD1, MafA, and Glut-2 at ×100 and ×400 magnification. Sections were counterstained with Gill's formulation no. 2 hematoxylin. (Please see http://dx.doi.org/10.2337/db07-0337 for a high-quality digital representation of this figure.)
