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A: Blocking the action of endogenous apoE in the brain with its antibody induces feeding even during the light phase. Data are means ± SE, n = 8, *P < 0.05, **P < 0.01 vs. control (apoE preabsorbed serum) group. B: The anorectic effect of apoE was attenuated by the infusion of its antibody in ad libitum–fed rats. n = 7, **P < 0.01 vs. saline group; #P < 0.05 vs. the apoE group. ApoE Ab, apoE antibody.
