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Histogram depicting the number of genes/probe sets in which expression was increased or reduced at P < 0.05 in NHE3−/− mice relative to their wild-type littermates (Student's t-test with Benjamini and Hochberg false discovery rate as multiple testing correction). Increasing stringency of analysis (2- to 10-fold change on x-axis) demonstrates the magnitude of change in colonic gene expression profile in NHE3−/− mice.
