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Sildenafil-mediated suppression of PE-induced contractions is diminished in Slo−/−. A and B: representative PE-induced contractions recorded from a Slo+/+ (left) and a Slo−/− (right) CCSM strip before (A) and after (B) adding sildenafil (SIL). C: summary of the SIL-mediated reduction of PE-induced contractions as shown in A and B; n, no. of CCSM strips; N, no. of mice; P < 0.01 vs. untreated (*) and vs. Slo+/+ + SIL (#).
