Table 2.

Preexposure echocardiographic parameters between 18- and 28-mo-old mice

Parameters	18 mo	28 mo	%Difference	t-test (P values)
BW, g	33.9±2.0	30.9±1.4	−8.9	0.22
LVEDD, mm	3.62±0.1	3.23±0.1	−10.8	0.01†
LVESD, mm	1.62±0.13	1.45±0.07	−10.5	0.25
PWTED, mm	0.97±0.02	0.97±0.03	0.0	0.86
FS, %	55.7±3.0	55.1±1.5	−1.1	0.86
RWT, %	27.1±1.0	30.3±1.4	11.8	0.07
HR, beats/min	625±14	613±10	−1.9	0.46

Data are means ± SE; n = 15 mice/age group.

^†P < 0.05, 28 mo vs. 18 mo.