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. 2008 May 7;295(1):R343–R354. doi: 10.1152/ajpregu.00115.2008

Fig. 4.

Fig. 4.

Bilateral MUSC into the DMH reverses the PGE2- or PGE2/skin cooling-evoked increases in BAT SNA but has no effect on those in tail CVC neuronal activity. A: PGE2 into the POA increased multiunit tail CVC neuronal activity, BAT SNA, and BAT temperature (TBAT). Bilateral MUSC into the DMH (arrowheads) promptly reversed the PGE2-evoked increase in BAT SNA but had no effect on tail CVC neuronal activity. MUSC into the rRPa (arrowhead) reduced tail CVC neuronal activity. Intravenous hexamethonium (HEX) eliminated the remaining tail CVC neuronal activity. TSK, skin temperature, TC, core temperature. B: PGE2 into the POA increased multiunit tail CVC neuronal activity, but had no effect on BAT SNA at TSK and TC necessary to reduce the basal CVC neuronal firing rate. Skin cooling elicited an increase in BAT SNA and TBAT. Bilateral MUSC into the DMH (arrowheads) reduced BAT SNA but had no effect on tail CVC neuronal activity. MUSC into the rRPa eliminated activity in both BAT SNA and tail CVC neurons. Vertical scale: 125 μv and 200 μv for BAT SNA in A and B, respectively.