FIG. 2.
The effects of PACAP-38 (1–30 µg i.t.) on the reflex bladder contractions under isovolumetric conditions in a spinal cord transected rat with intact hypogastric nerves. Note that larger doses (10 µg and 30 µg) of PACAP-38 increased the bladder contraction amplitude and duration and decreased the frequency of contractions, whereas smaller dose (1 µg) had little effect on these parameters.