TABLE 1.

Effects of Intrathecal Administration of PACAP on Reflex Bladder Activity of Spinal Cord Transected Rats with Intact or Bilaterally Sectioned Hypogastric Nerves, under Isovolumetric Conditions

	BCA	BCD	BCF
	(cm H2O)	(s)	(contractions/min)
Transected SC + Intact HGN
PACAP (10 µg) (n=7)
before	24.5 ± 7.7	50 ± 7	1.08 ± 0.24
after	37.7 ± 9.8	102 ± 25	0.76 ± 0.23*
PACAP (30 µg) (n=5)
before	16.7 ± 3.0	47 ± 10	1.49 ± 0.30
after	49.1 ± 10.6*	141 ± 56	0.38 ± 0.21**
Transected SC + Sectioned HGN
PACAP (10 µg) (n=7)
before	22.4 ± 3.2	53 ± 6	0.94 ± 0.08
after	36.2 ± 2.7**	90 ± 19*	0.59 ± 0.12*
PACAP (30 µg) (n=4)
before	22.9 ± 5.2	93 ± 37	0.71 ± 0.18
after	67.6 ± 15.1*	276 ± 66	0.18 ± 0.04*

Note. BCA, bladder contraction amplitude; BCD, bladder contraction duration; BCF, bladder contraction frequency; SC, spinal cord; HGN, hypogastric nerves.

^*P<0.05

^**P<0.01 (paired t test), compared “after” to “before” the i.t. injection of PACAP.