Characteristics of the fat samples obtained from patients with amyloidoses
The degree of amyloid infiltration in the abdominal subcutaneous fat aspirates was assessed by Congo red staining on a scale from 0 to 3. Positives designate the detection of fibrillar deposits. AL patients were typed by demonstration of a plasma cell dyscrasia followed by sequencing of the monoclonal component as described under “Experimental Procedures.” ATTR patients were typed by direct genomic DNA sequencing of the indicated TTR mutation.