Skip to main content
. 2008 Aug 8;283(32):22233–22243. doi: 10.1074/jbc.M802074200

TABLE 4.

Comparison of relative single channel lifetimes of gramicidin channels having Trp → 1-Me-Trp and Trp → Phe substitutions

Substitution position
Normalized lifetimea
Trp → 1-Me-Trpb Trp → Phec
None 1.0 1.0
9 1.1 1.2
11 1.8 2.7
13 1.2 1.0
15 1.3 1.0
9, 11, 13, 15 3.2 0.4d
a

Values relative to lifetime of native gA channels.

b

Data from Table 3, measured in 1.0 m CsCl.

c

Data from Ref. 27, measured under conditions of 1.0 m NaCl and 200 mV.

d

Data from Ref. 75, measured under conditions of 1.0 m CsCl and 200 mV.