TABLE 2.

Labeling from 40% NaH¹³CO₃ of liver CAC and gluconeogenic intermediates

Livers were perfused with buffer containing 40% NaH¹³CO₃ + 5 mm lactate or 2 mm pyruvate ± 0.3 mm MPA or 0.5 mm AOA. Labeling data are expressed in mole percent enrichments (mean ± S.E., n = 4–7). Most metabolites are only M1-labeled, except for citrate and glucose that are M1- and M2-labeled. The total labeling of citrate and glucose was calculated using Equation 2.

^ap < 0.05 compared with control.

^bp < 0.05 compared with the measured labeling of glucose.

^c Data represent p < 0.05 compared with PEP in the same group.

^dp < 0.05 between calculated average of TP to measured average of TP (citrate and glucose total labeling was calculated as (m1 + 2·m2) MPE).

^ep < 0.05 compared with C6 of citrate.