TABLE 3.

Summary of expression profiles after 1 and 3 hours of 3AT-induced histidine starvation

Type of expression	-Fold change	No. of responding genes
				WT		int6–		gcn2–		hri1– hri2– gcn2–
		1 h	3 h	1 h	3 h	1 h	3 h	1 h	3 h
Induced	≥10	24	52	15	97	23	76	22	75
	≥4	106	131	125	381	98	185	80	179
	≥2	356	502	521	1056	406	593	377	472
	≥2 (% of total)	7.2	10.5	10.4	21.0	8.0	11.7	7.5	9.4
	<2	2098	1915	2011	1409	2279	1907	1976	1797
Repressed	≥10	0	1	3	7	0	0	1	4
	≥4	9	31	11	94	6	24	12	31
	≥2	121	385	244	872	345	333	169	221
	≥2 (% of total)	2.4	8.1	4.9	17.3	6.8	6.6	3.3	4.4
	<2	2395	1974	2236	1695	2049	2239	2535	2557
Total open reading frames considered		4970	4776	5012	5032	5079	5072	5057	5047