Table 2.
Gene | Fold-decrease1 | Description2 |
AAD4 | 11 | Putative aryl-alcohol dehydrogenase. Involved in oxidative stress response. |
TSA2 | 6.5 | Stress induced thioredoxin peroxidase. |
CCS1 | 5.5 | Copper chaperone for superoxide dismutase Sod1. Involved in oxidative stress protection. |
AAD6 | 4.4 | Putative aryl-alcohol dehydrogenase. Involved in oxidative stress response. |
GPX2 | 3.6 | Phospholipid hydroperoxide glutathione peroxidase. Protects cells from peroxides. |
SSA4 | 3.3 | Heat shock protein that is highly induced upon stress. Role in SRP-dependent cotranslational protein-membrane targeting. |
GRX2 | 3.1 | Glutaredoxin, thioltransferase, glutathione-dependent disulfide oxidoreductase. Maintains redox state of target proteins. |
RHR2 | 3.0 | DL-glycerol-3-phosphatase. Induced by anaerobic and osmotic stress. |
ALD2 | 2.4 | Aldehyde dehydrogenase. Stress induced. |
TRX2 | 2.4 | Thioredoxin isoenzyme. Protects cells against oxidative stress. |
GRE2 | 2.4 | 3-methylbutanal reductase and methylglyoxal reductase. Stress induced. |
SRX1 | 2.4 | Sulfiredoxin. Contributes to oxidative stress resistance. |
ALD3 | 2.3 | Cytoplasmic aldehyde dehydrogenase. Stress induced. |
LSP1 | 2.3 | Component of eisosomes. Null mutants show activation of Pkc1p/Ypk1p stress pathways. |
PST2 | 2.2 | Similarity to flavodoxin-like proteins. Induced by oxidative stress. |
CMK1 | 2.2 | Calmodulin-dependent protein kinase. May play a role in stress response. |
DAK1 | 2.0 | Dihydroxyacetone kinase. Involved in stress adaptation. |
1 Decrease in gene expression from microarray analysis [9], tra1SRR3413 versus TRA1
2 Modified from the Saccharomyces Genome Database