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. 2008 Aug 13;3(8):e2965. doi: 10.1371/journal.pone.0002965

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Sohal et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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349 UniGene IDs were identified as being consistently expressed amongst the normal hematopoietic cells and differentially expressed between hematopoietic and non-hematopoietic cells. Genes enriched in hematopoietic progenitor and stem cell datasets were involved in important functional pathways in the cell, including drug metabolism, hematological system development, cell signaling and cancer and cell death, as shown in the bar graph alongside. One such network is shown, which includes the GATA2, Cyclin E and SMARCE1 genes. B: Heatmap of “stemness” genes. 349 Unigene IDs were identified as being consistently expressed amongst the normal hematopoietic cells and differentially expressed between hematopoietic and non-hematopoietic cells. Out of these, 176 genes were enriched in HSC datasets when compared to other tissue types.