Table 6. Genes quiescent in HSC progenitor cells* .
Major functions | Well-annotated genes |
Skeletal and Muscular System Development, Function and Disorders, Genetic Disorders | ADD1, APBB3, ARHGAP1, ATP2A2, BCL2L2, BGN, CALCOCO1, CALD1, CALM1, COL18A1, COL6A1, DDR1, ESRRA, FMOD, MYH9, NCOA1, PFN2, PXN, RHOC, SQSTM1, TPM1 |
Cellular Assembly and Organization, Cellular Function and Maintenance, Cell Signaling | APP, CADM1, CD59, CLSTN1, ERBB2, F8, FLOT1, GDI1, IKBKG, MAPK13, MYO1C, NDRG2, NFE2L1, PTRF, RAB5B, RAB5C, SFRP1, SHC1, SPTAN1, WFS1 |
Protein Degradation, Cellular Movement, Cell Morphology | ARF3, ARFIP2, CES2, COL1A1, CTNND1, EIF4G1, GSK3A, GSTA1, GSTM2, KIF5C, MFN2, MMP14, PAPSS2, PCDHGC3, PTPRF, SDC1, TIMP3, TSPAN3 |
Others | CDC42EP4, CHST10, DEFB1, FKBP1A, HDLBP, LPP, S100A13, TEGT, AKAP1, CLOCK, JAM3, PCTK1, TLE2, TMPRSS6, TNFAIP1, TRIP10, USP13, SPOCK2 |
Some important genes differentially under-expressed in hematopoietic progenitors, as compared to non-hematopoietic tissues