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. 2008 Aug 20;3(8):e2976. doi: 10.1371/journal.pone.0002976

Table 1. Electrophysiological properties of Cav3.1, Cav3.3, and their deletion mutants.

Current Density Activation Inactivation Po estimate
Gmax sem V0.5 sem k sem n V0.5 sem k sem n G/Q sem n
(nS/pF) (mV) (mV) (mV) (mV)
Cav3.1 WT 2.9 ±0.3 −44.6 ±0.7 5.8 ±0.2 19 −77.7 ±0.7 −5.0 ±0.2 15 0.33 ±0.05 9
GD1–2 4.5 ±0.8* −62.2 ±5.8** 4.6 ±0.2*** 9 −91.0 ±1.6*** −4.0 ±0.1*** 9 0.94 ±0.19** 6
GD3–5 6.0 ±1.2** −56.0 ±1.2*** 4.0 ±0.3*** 8 −81.2 ±1.5* −4.2 ±0.2* 8 0.31 ±0.03 7
Cav3.3 WT 2.3 ±0.3 −40.2 ±0.8 5.8 ±0.2 17 −68.6 ±0.7 −5.5 ±0.5 9 0.16 ±0.02 9
ID1–2 2.4 ±0.5 −51.6 ±1.4*** 5.9 ±0.2 9 −83.0 ±1.1*** −4.3 ±0.2 6 0.32 ±0.04*** 6
ID3–5 1.6 ±0.3 −43.2 ±1.5 6.6 ±0.2* 8 −76.1 ±1.7*** −5.1 ±0.2 5 0.17 ±0.01 6

The Gmax and V0.5 of activation were determined from the I-V protocol, and therefore have the same number of cells (n) in each measurement. The G/Q ratio was calculated for each individual cell, and then averaged. Statistical significance is denoted with asterisks, where three asterisks indicates P<0.001, two for P<0.01, and one for P<0.05.