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. Author manuscript; available in PMC: 2009 Jul 1.
Published in final edited form as: Mol Immunol. 2008 May 23;45(12):3401–3410. doi: 10.1016/j.molimm.2008.04.007

Fig. 1.

Fig. 1

Abnormal thymocyte development in neonatal Gαi-deficient mice. Thymi (A), spleen (B) and bone marrow (C) were isolated from wild type (WT) and Gαi2−/− and Gαi3−/− mice at 3 days of age. Single cell suspensions were prepared and counted. T cell numbers in the spleen were obtained in the basis of percentages of CD3+ cells identified by flow cytometry. Each symbol in A, C and D relates to data obtained from a single animal and the data in B and E are the means ± standard deviation (SD) of 6 (WT), 8 (Gαi2−/−) and 7 (Gαi3−/−) mice. *, p<0.01 and **, p<0.001 in the presence or absence of Gαi2 or Gαi3.