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. 1975 Jun;51(596):412–416. doi: 10.1136/pgmj.51.596.412

Secondary syphilis presenting with jaundice

B K Bhowmick, B Simpson, S P B Way
PMCID: PMC2496086  PMID: 1215259

Abstract

A patient with secondary syphilis presenting with jaundice is reported. Hepatic histology showed evidence of non-specific granuloma and active hepatitis but no cholestasis. This has been treated successfully with antisyphilitic therapy. The possibility of syphilitic pancreatitis and diabetes mellitus is discussed. The importance of serological tests for syphilis in jaundice of obscure origin is emphasized.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Baker A. L., Kaplan M. M., Wolfe H. J., McGowan J. A. Liver disease associated with early syphilis. N Engl J Med. 1971 Jun 24;284(25):1422–1423. doi: 10.1056/NEJM197106242842507. [DOI] [PubMed] [Google Scholar]
  2. Dordal E., Glagov S., Kirsner J. B. Hepatic lesions in chronic inflammatory bowel disease. I. Clinical correlations with liver biopsy diagnoses in 103 patients. Gastroenterology. 1967 Feb;52(2):239–253. [PubMed] [Google Scholar]
  3. KLATSKIN G., YESNER R. Hepatic manifestations of sarcoidosis and other granulomatous diseases; a study based on histological examination of tissue obtained by needle biopsy of the liver. Yale J Biol Med. 1950 Dec;23(3):207–248. [PMC free article] [PubMed] [Google Scholar]
  4. Lee R. V., Thornton G. F., Conn H. O. Liver disease associated with secondary syphilis. N Engl J Med. 1971 Jun 24;284(25):1423–1425. doi: 10.1056/NEJM197106242842508. [DOI] [PubMed] [Google Scholar]
  5. McCracken J. D., Hall W. H., Pierce H. I. Nephrotic syndrome and acute hepatitis in secondary syphilis. Mil Med. 1969 Sep;134(9):682–686. [PubMed] [Google Scholar]
  6. Parker J. D. Uncommon complications of early syphilis. Hepatitis, periostitis, iritis with papillitis, and meningitis. Br J Vener Dis. 1972 Feb;48(1):32–36. doi: 10.1136/sti.48.1.32. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Sherlock S. The liver in secondary (early) syphilis. N Engl J Med. 1971 Jun 24;284(25):1437–1438. doi: 10.1056/NEJM197106242842513. [DOI] [PubMed] [Google Scholar]

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