Abstract
This article reviews the current place of erythromycin in antibiotic therapy. Overall, erythromycin is thought to be underused because: (1) the fear of resistance has been exaggerated; (2) significant toxicity has been associated with only one derivative (the estolate); (3) newer antibiotics have very rarely been demonstrated to be superior to erythromycin. Erythromycin has an important place in treating acute upper and lower respiratory tract infections, acute otitis media, sinusitis, skin and soft tissue, osteomyelitis, prostatitis, infections due to Mycoplasma spp. and Chlamydia organisms, and infections due to anaerobes.
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Selected References
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- Blockey N. J., McAllister T. A. Antibiotics in acute osteomyelitis in children. J Bone Joint Surg Br. 1972 May;54(2):299–309. [PubMed] [Google Scholar]
- Burgess H. A., Evans R. J. Failure of cephaloridine in a case of staphylococcal endocarditis. Br Med J. 1966 Nov 19;2(5524):1244–1244. doi: 10.1136/bmj.2.5524.1244. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Lacey R. W. Genetic basis, epidemiology, and future significance of antibiotic resistance in Staphylococcus aureus: a review. J Clin Pathol. 1973 Dec;26(12):899–913. doi: 10.1136/jcp.26.12.899. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Manners B. T., Grob P. R., Beynon G. P., Gibbs F. J. An investigation of antibiotic resistance of Staphylococcus aureus in general practice. Practitioner. 1976 Apr;216(1294):439–442. [PubMed] [Google Scholar]
- Maskell R., Okubadejo O. A., Payne R. H. Thymine-requiring bacteria associated with co-trimoxazole therapy. Lancet. 1976 Apr 17;1(7964):834–835. doi: 10.1016/s0140-6736(76)90482-7. [DOI] [PubMed] [Google Scholar]
- Oriel J. D., Reeve P., Wright J. T., Owen J. Chlamydial infection of the male urethra. Br J Vener Dis. 1976 Feb;52(1):46–51. doi: 10.1136/sti.52.1.46. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Peach S. Antibiotic-disc tests for rapid identification of non-sporing anaerobes. J Clin Pathol. 1975 May;28(5):388–391. doi: 10.1136/jcp.28.5.388. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Ridgway G. L., Owen J. M., Oriel J. D. A method for testing the antibiotic susceptibility of Chlamydia trachomatis in a cell culture system. J Antimicrob Chemother. 1976 Mar;2(1):71–76. doi: 10.1093/jac/2.1.71. [DOI] [PubMed] [Google Scholar]