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. 2008 Aug 20;3(8):e2977. doi: 10.1371/journal.pone.0002977

Figure 6. The glutamate transporter GLT-1 is expressed in virally infected astrocytes.

Figure 6

Representative confocal images of brain sections stained with markers specific for activated astrocytes (GFAP, magenta), glutamate transporter (GLT-1, green), viral infection (TK, red), and nuclei (DAPI, blue). Merge 1 displays GFAP and GLT-1 immunoreactivity to show expression of GLT-1 in astrocytes; Merge 2 shows TK and GLT-1 immunoreactivity to indicate GLT-1 expression in virally infected cells; and Merge 3 depicts GFAP, GLT-1, and TK immunoreactivity to demonstrate expression of GLT-1 in virally infected astrocytes. White rectangles show a higher magnification of a triple-labeled process. Note that GLT-1 is expressed in astrocytes, and appears localized to the membrane surrounding GFAP filaments.