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. 2008 Jun 26;8:41. doi: 10.1186/1471-2288-8-41

Table 3.

Systematic reviews on NPWT: Search strategies

Systematic review Search terms Literature sources Search date*

MEDLINE EMBASE The Cochrane Library CINAHL Others
Samson/AHRQ 2004 [29] Vacuum-assisted closure:
- "topical negative pressure"
- "sub-atmospheric pressure therapy" (also "subatmospheric")
- "sub-atmospheric pressure dressing" (also "subatmospheric")
- "vacuum sealing"
- "vacuum assisted closure"
- "negative pressure dressing"
- "negative pressure therapy"
- "foam suction dressing"
- "vacuum compression"
- "vacuum pack"
- "sealed surface wound suction"
- "sealing aspirative therapy"
Wounds:
- "wound*"
- "ulcer*"
- "decubit*"
- "incision*"
- "dressing"
- "free flap"
- "skin graft*"
- "skin transplantation"
- "degloving injuries"
- "degloving injury"
+
MEDLINE via PubMed
+ +
CENTRAL
- -
Manufacturers
6/2004§
Costa/MUHC TAU 2005[30] "vacuum" or "vacuum-assisted" or "VAC" or "negative pressure" or "suction dressing" or "subatmospheric" or "sub-atmospheric" or "subatmospheric pressure" or "NPWT" and "wound healing"|| +
PubMed
+ +
CDSR
- -
HTA agencies (CHSPR, MCHP, ICES, INAHTA)
- Screening of reference lists of primary studies and secondary publications
3/2005
IQWiG 2006 [8] Search strategies according to databases (published on pages 114 to 130 of the IQWiG review [8]) +
Ovid MEDLINE, Ovid MEDLINE In-Process and Other Non-Indexed Citations
+
Ovid EMBASE
+
CENTRAL; CDSR; DARE; HTA
+
Ovid CINAHL
-
Trial registries (ClinicalTrials.gov, National Research Register)
- Manufacturers
- Authorities
- Conference proceedings
- Authors of articles and conference abstracts
- Screening of reference lists of secondary publications
5/2005
Pham/ASERNIP-S 2006 update [31] (vacuum or suction) and (wound healing), (vacuum assisted or vacuum-assisted) and (wound or closure), topical negative pressure, (subatmospheric or sub-atmospheric) and pressure +
MEDLINE; PREMEDLINE; PubMed
+ +
The Cochrane Library
- -
Current Contents
- Trial registries (ClinicalTrials.gov, National Research Register)
- The York (UK) Centre for Reviews and Dissemination
- Grey literature reports
- Relevant online journals
- Vacuum therapy website (vacuumtherapy.co.uk)
- The Internet
10/2004 New RCTs: 7/2005**
OHTAC 2006 (update) [32] -
wound healing
- foot ulcer or skin ulcer or varicose ulcer or leg ulcer
- wounds, non penetrating
- chronic and ulcer or wound
- leg or foot arterial or diabetic and ulcer or wound
- suction
- pressure
- vacuum
- vacuum assisted closure or V.A.C. therapy
- negative pressure
- topical negative pressure
- subatmospheric pressure therapy
+
MEDLINE, MEDLINE In-Process and Non-Indexed Citations
+ +
CDSR
- -
HTA agencies (INAHTA)
- Vacuum therapy website (vacuumtherapy.co.uk)
3/2006

*End of search period.

"The intersection of the vacuum-assisted closure terms and wound terms served as the initial pool of references. These were cross-referenced with the terms for randomized trials compiled by the Cochrane Collaboration...." For further details, please see Appendix A [29].

Request for "lists of published, randomized, controlled trials (RCTs), published abstracts of RCTs within the past 2 years, and published articles on study design, or protocols of any RCTs (published or in press)" [29].

§CENTRAL: 2003 ("through issue number 4", [29]).

|| "Health technology agencies databases were also searched for technology assessment reports, systematic reviews and economic studies with the keywords 'vacuum', 'subatmospheric pressure', and 'sub-atmospheric pressure' used individually" [30].

Unpublished data from primary studies were only to be considered in the review if comprehensive study information (e.g. a clinical study report) was available.

** "Updated searches were performed in July 2005 to include any new RCTs" [31].

AHRQ: Agency for Healthcare Research and Quality; ASERNIP-S: Australian Safety and Efficacy Register of New Interventional Procedures – Surgical; CDSR: Cochrane Database of Systematic Reviews; CENTRAL: Cochrane Central Register of Controlled Trials; CHSPR: Centre for Health Services and Policy Research; DARE: Database of Abstracts of Reviews of Effects; CINAHL: Cumulative Index to Nursing and Allied Health Literature; EMBASE: Excerpta Medica Database; HTA: health technology assessment; CRD: Centre for Reviews and Dissemination; INAHTA: International Network of Agencies for Health Technology Assessment; IQWiG: Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen (Institute for Quality and Efficiency in Health Care); MCHP: Manitoba Centre for Health Policy; MUHC TAU: McGill University Health Centre Technology Assessment Unit; MEDLINE: Medical Literature Analysis and Retrieval System Online; NPWT: negative pressure wound therapy; OHTAC: Ontario Health Technology Advisory Committee; RCT: randomised controlled trial; VAC: vacuum-assisted closure.