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. 2008 Aug 7;118(9):3132–3142. doi: 10.1172/JCI35700

Figure 1. Expression of γc and phosphorylation status of JAK3 in blast cells.

Figure 1

(A) Flow cytometric analysis of γc expression on P7 and P10 cells revealed a normal range of expression on blast cells of P7 at M+68 and P10 at M+33 as well as on normal P7 T cells recovered at M+84, after 16 months of chemotherapy. (B) Tyrosine phosphorylation status of JAK3 in P7 and P10 leukemic blasts after stimulation with 10 ng/ml IL-7 (+) or without stimulation (–; resting cells). Top: Immunoblot used an antibody to phosphotyrosine. Bottom: The same prestripped blot was reprobed with an antibody to JAK3.