Table 2.
Genotype and allele frequencies of the polymorphism among AMI, CHD, and ischemic stroke cases and sub-cohort of the Prospect – Epic cohort
| Genotype/allele | Acute myocardial infarction | Coronary heart disease | Ischemic stroke | Sub-cohort | ||||
|---|---|---|---|---|---|---|---|---|
| No. | % | No. | % | No. | % | No. | % | |
| No. of subjects | 71 | 211 | 49 | 1519 | ||||
| Genotype | ||||||||
| P/P | 61 | 85.9 | 167 | 79.1 | 38 | 77.6 | 1143 | 75.2 |
| P/A | 10 | 14.1 | 41 | 19.4 | 10 | 20.4 | 346 | 22.8 |
| A/A | 0 | 0.0 | 3 | 1.4 | 1 | 2 | 30 | 2 |
| Allele | ||||||||
| Pro | 132 | 93.0 | 375 | 88.9 | 86 | 87.8 | 2632 | 86.6 |
| Ala | 10 | 7.0 | 47 | 11.1 | 12 | 12.2 | 406 | 13.4 |
| χ2 = 4.77 | χ2 = 1.61 | χ2 = 0.10 | ||||||
| Df = 1 | df = 1 | df = 1 | ||||||
| p = 0.03 | p = 0.20 | p = 0.75 | ||||||