Table 1.

Inherited disorders caused by ion channelopathies

		Rhythm	Inheritance	Locus	Ion channel	Gene
Long QT syndrome	(RW)	TdP	AD
	LQT1			11p15	IKs	KCNQ1, KvLQT1
	LQT2			7q35	IKr	KCNH2, HERG
	LQT3			3p21	INa	SCN5A, Nav1.5
	LQT4			4q25		ANKB, ANK2
	LQT5			21q22	IKs	KCNE1, minK
	LQT6			21q22	IKr	KCNE2, MiRP1
	LQT7	(Andersen-Tawil syndrome)		17q23	IK1	KCNJ2, Kir 2.1
	LQT8	(Timothy syndrome)		6q8A	ICa	CACNA1C, Cav1.2
	LQT9			3p25	INa	CAV3, Caveolin-3
	LQT10			11q23.3	INa	SCN4B. Navb4
LQT syndrome (JLN)		TdP	AR	11p15	IKs	KCNQ1, KvLQT1
				21q22	IKs	KCNE1, minK
Brugada syndrome	BrS1	PVT	AD	3p21	INa	SCN5A, Nav1.5
	BrS2	PVT	AD	3p24	INa	GPD1L
	BrS3	PVT	AD	12p13.3	ICa	CACNA1C, CaV1.2
	BrS4	PVT	AD	10p12.33	ICa	CACNB2β, Cavβ2b

AD — autosomal dominant; AR — autosomal recessive; JLN — Jervell and Lange-Nielsen; LQT — long QT; RW — Romano-Ward; TdP — torsade de pointes; VF — ventricular fibrillation; VT — ventricular tachycardia; PVT — polymorphic VT