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. Author manuscript; available in PMC: 2009 Jul 1.
Published in final edited form as: Microb Pathog. 2008 Mar 25;45(1):70–78. doi: 10.1016/j.micpath.2008.03.002

Table 2.

The ospC operator helps B. burgdorferi evade clearance by OspC MAba

No. of cultures positive/Total no. of specimens examined
Clone Treatment received Heart Joint Skin All sites
ΔospC/FL/1 mouse IgG 5/5 5/5 5/5 15/15
OspC MAb 3/5 5/5 4/5 12/15
Bp-C/1 mouse IgG 5/5 5/5 5/5 15/15
OspC MAb 0/5 0/5 0/5 0/15
Bp-C/2 mouse IgG 5/5 5/5 5/5 15/15
OspC MAb 0/5 0/5 0/5 0/15
Co1-Bp-C/1 mouse IgG 5/5 5/5 5/5 15/15
OspC MAb 0/5 5/5 3/5 8/15
Co1-Bp-C/2 mouse IgG 5/5 5/5 5/5 15/15
OspC MAb 0/5 5/5 3/5 8/15
Co2-Bp-C/1 mouse IgG 5/5 5/5 5/5 15/15
OspC MAb 0/5 5/5 2/5 7/15
Co2-Bp-C/2 mouse IgG 5/5 5/5 5/5 15/15
OspC MAb 0/5 5/5 3/5 8/15
a

Groups of 10 BALB/c SCID mice were inoculated with the clone ΔospC/FL/1, Bp-C/1, Bp-C/2, Co1-Bp-C/1, Co1-Bp-C/2, Co2-Bp-C/1 or Co2-Bp-C/2. Three weeks later, five animals from each group received a single dose of either OspC MAb or murine IgG as a control and were sacrificed within 1 week. Heart, tibiotarsal joint and skin specimens were harvested and cultured for spirochetes in BSK-H complete medium.