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. Author manuscript; available in PMC: 2009 Jul 1.
Published in final edited form as: Microb Pathog. 2008 Mar 25;45(1):70–78. doi: 10.1016/j.micpath.2008.03.002

Table 3.

The ospC operator facilitates immune evasion of B. burgdorferia

No. of cultures positive/Total no. of specimens examined
Clone Heart Joint Skin All sites
ΔospC/FL/1 10/10 10/10 10/10 30/30
Bp-C/1 0/5 0/5 3/5 3/15
Bp-C/2 0/5 0/5 4/5 4/15
Co1-Bp-C/1 3/5 5/5 5/5 13/15
Co1-Bp-C/2 3/5 4/5 5/5 12/15
Co2-Bp-C/1 4/5 2/5 5/5 11/15
Co2-Bp-C/2 4/5 3/5 5/5 12/15
a

Groups of five or 10 BALB/c mice were inoculated with the clone ΔospC/FL/1, Bp-C/1, Bp-C/2, Co1-Bp-C/1, Co1-Bp-C/2, Co2-Bp-C/1 or Co2-Bp-C/2. Mice were sacrificed 4 months post-inoculation. Heart, tibiotarsal joint and skin specimens were harvested and cultured for spirochetes in BSK-H complete medium. Fisher’s exact test P values were 0.01 and 1.2 × 10−4 between the genotypes Bp-C and Co1-Bp-C in heart and joint tissues, 7.1 × 10−4 and 0.03 between Bp-C and Co2-Bp-C in heart and joint tissues, and 0.63 and 0.14 between Co1-Bp-C and Co2-Bp-C in heart and joint tissues, respectively.