Table 1.
Numbers represent mean absolute numbers (± SEM) of cocaine infusions, break points and active bar presses for each treatment group. Values for the Baseline condition represent the numbers obtained on the day before the microinjection test. Values under Recovery represent the numbers obtained on the day after the microinjection.
| Group Mean (± SEM) | Baseline | CART Microinjection | Recovery | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Coc Infusions | Break Point | Bar Press | Coc Infusions | Break Point | Bar Press | Coc Infusions | Break Point | Bar Press | |
| aCSF | 16 (1) | 176 (64) | 669 (153) | 15 (2) | 146 (46) | 679 (209) | 15 (1) | 169 (66) | 729 (234) |
| 0.25 CART | 13 (1) | 65 (14) | 323 (69) | 12 (1) | 62 (22) | 322 (105) | 11 (1) | 39 (3) | 269 (57) |
| 1.0 CART | 16 (1) | 137 (70) | 754 (132) | 11 (2) | 77 (74) | 387 (152) | 16 (1) | 119 (36) | 749 (123) |
| 2.5 CART | 15 (1) | 113 (20) | 547 (130) | 8 (2) * | 40 (13)* | 246 (79) | 15 (2) | 141 (138) | 609 (286) |
Asterisk indicates significant difference from aCSF control (P<0.05).