Table 1.
Antagonist | IC50 (nM) | nH | IC90 (nM) | CE50 (nM) | CE50/IC90 |
---|---|---|---|---|---|
(+)-tubocurarine | 24 ± 2 | 1.03 ± 0.07 | 286 ± 70 | 606 − 982 | 1.3 − 2.1 |
metocurine | 18 ± 2 | 1.04 ± 0.11 | 149 ± 32 | ||
pancuronium | 6.3 ± 0.8 | 0.95 ± 0.08 | 94 ± 28 | 154 | 1.6 |
vecuronium | 15 ± 2 | 1.03 ± 0.12 | 129 ± 38 | 168 − 190 | 1.3 − 1.5 |
cisatracurium | 10 ± 1 | 1.02 ± 0.09 | 88 ± 18 | 135 − 169 | 1.5 − 1.9 |
rocuronium | 17 ± 2 | 0.67 ± 0.05 | 472 ± 95 | 1250−1600 | 2.6 − 3.4 |
atracurium | 17 ± 2 | 0.56 ± 0.09 | 744 ± 120 |