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. Author manuscript; available in PMC: 2009 Jul 1.
Published in final edited form as: Bioconjug Chem. 2008 Jun 20;19(7):1439–1447. doi: 10.1021/bc800050x

Table 5.

Biodistribution of ligands radiolabeled with 153Gd in Non-Tumor Bearing Athymic Mice

Ligand Tissue Timpoints (hr)
0.50 1.00 4.00 8.00 24.00
C-NE3TA Blood 1.41 ± 0.57 0.20 ± 0.08 0.00 ± 0.00 0.00 ± 0.00 0.00 ± 0.00
Liver 1.74 ± 0.69 0.58 ± 0.22 0.03 ± 0.01 0.02 ± 0.00 0.02 ± 0.01
Spleen 0.50 ± 0.37 0.24 ± 0.05 0.02 ± 0.00 0.02 ± 0.00 0.01 ± 0.01
Kidney 4.28 ± 1.33 1.13 ± 0.12 0.52 ± 0.04 0.38 ± 0.06 0.16 ± 0.11
Lung 0.91 ± 0.28 0.32 ± 0.09 0.03 ± 0.00 0.02 ± 0.00 0.01 ± 0.01
Heart 0.43 ± 0.16 0.14 ± 0.06 0.01 ± 0.00 0.01 ± 0.00 0.13 ± 0.27
Femur 0.43 ± 0.14 1.30 ± 0.58 0.02 ± 0.01 0.02 ± 0.00 0.01 ± 0.00
C-NETA Blood 1.33 ± 0.32 0.39 ± 0.07 0.05 ± 0.02 0.03 ± 0.01 0.01 ± 0.01
Liver 2.79 ± 0.24 2.41 ± 0.34 3.19 ± 0.54 4.01 ± 0.53 2.98 ± 0.44
Spleen 0.63 ± 0.14 0.27 ± 0.05 0.31 ± 0.04 0.20 ± 0.02 0.24 ± 0.02
Kidney 3.37 ± 0.23 2.21 ± 0.38 2.70 ± 0.26 2.63 ± 0.43 2.18 ± 0.14
Lung 1.39 ± 0.20 0.69 ± 0.10 0.47 ± 0.09 0.40 ± 0.12 0.31 ± 0.03
Heart 0.82 ± 0.21 0.51 ± 0.18 0.31 ± 0.02 0.27 ± 0.07 0.25 ± 0.04
Femur 2.27 ± 0.23 1.79 ± 0.24 1.96 ± 0.28 2.06 ± 0.22 2.31 ± 0.40

Values are the percent injected dose per gram(% ID/g) ± standard deviation