Table 1.
Conjugate | Peptide |
---|---|
PKI | CNELALKLAGLDINKT |
MIX | CTKNILDGALKLALNE |
REV | CLPPLERLTLD |
BSA-R | CLPPLERLTL |
M10 | CLPPDLRLTLD |
Peptides PKI, MIX, REV, and M10 were conjugated to HSA and used in injection experiments as described in the text. BSA-R refers to the Rev-NES peptide conjugate used by Fischer et al. (3). Leucine residues shown to be critical for function of the nuclear export signals (1, 2, 4) are in bold. Mix is a scrambled PKI NES.