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. 2008 Aug 20;3(8):e2975. doi: 10.1371/journal.pone.0002975

Figure 2. Frequency of circulating influenza-specific ASC after LAIV or TIV vaccination.

Figure 2

Influenza-specific IgA ASC and IgG ASC were measured with a direct ELISPOT assay at days 7–9 after LAIV ('05-LAIV) or TIV ('05-TIV) vaccination. A: Influenza-specific IgA and IgG ASC in all subjects after administration of '05-LAIV or '05-TIV. B: Influenza-specific IgA and IgG ASC after '05-LAIV or '05-TIV in the three sub-groups based on influenza vaccination status in the prior year: TIV ('04-T), LAIV ('04-L), or no vaccination ('04-N). The dashed-bars in each graph indicate the geometric mean values. **, P<.01 unpaired t-test (A) or significant difference after adjustment for multiple comparisons (B). *, result with a P value of <.05 in an individual test but not significant after adjustment for multiple comparisons (B).