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. 2008 Aug 20;3(8):e3020. doi: 10.1371/journal.pone.0003020

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Lee et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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(A) PNN density increases significantly between P10 and P14 within the entire neostriatum; after P14, PNN density levels off and remains consistent into adulthood (one-way ANOVA, Tukey-Kramer test; F(5, 48) = 142.14, P<<0.00001). Bar indicates significant increase in PNN density between P10 and P14. (B) PNN density is significantly greater in matrix compared to striosomes for all ages after P14 (Two-way ANOVA, age and subregion as factors; F(5, 96) = 112.8, P<<0.00001 across ages; F(1, 96) = 236.62, P<<0.00001 across subregions; F(5, 96) = 20.15, P<<0.00001 for interactions between age and subregion). (**) indicates significance levels of P<<0.00001.