Table 3.
Distribution of outcome variables by area of intervention at follow-up in Hyderabad nutrition trial
| No | Mean (SD) | Mean difference* (95% CI) (control minus intervention) | ||
|---|---|---|---|---|
| Intervention | Control | |||
| Body size and composition | ||||
| Height (mm) | 1120 | 1559 (83) | 1549 (82) | −10.0 (−18.7 to −1.4); P=0.024 |
| Body mass index (kg/m2) | 1120 | 17.1 (2.0) | 17.3 (2.4) | 0.27 (−0.08 to 0.61); P=0.1 |
| Fat mass index (kg/m2) | 1120 | 2.6 (1.3) | 2.6 (1.5) | −0.02 (−0.23 to 0.19); P=0.8 |
| Fat-free mass index (kg/m2) | 1120 | 14.5 (1.4) | 14.8 (1.6) | 0.29 (0.01 to 0.57); P=0.043 |
| Central-peripheral skinfold ratio | 1120 | 1.48 (0.25) | 1.47 (0.25) | −0.01 (−0.06 to 0.05); P=0.8 |
| Cardiovascular physiology | ||||
| Systolic blood pressure (mm Hg) | 1118 | 108.7 (10.3) | 109.6 (10.0) | 0.83 (−1.44 to 3.11); P=0.5 |
| Diastolic blood pressure (mm Hg) | 1118 | 62.5 (6.5) | 62.2 (6.5) | −0.23 (−1.70 to 1.25); P=0.8 |
| Augmentation index (%) | 862 | 2.5 (11.4) | 5.6 (9.1) | 3.16 (0.8 to 5.51); P=0.011 |
| Lipid profile | ||||
| Total cholesterol (mmol/l) | 1050 | 3.45 (0.69) | 3.45 (0.67) | −0.00 (−0.12 to 0.12); P=1.0 |
| LDL cholesterol (mmol/l) | 1050 | 2.05 (0.60) | 2.04 (0.59) | −0.02 (−0.13 to 0.09); P=0.8 |
| HDL cholesterol (mmol/l) | 1050 | 0.99 (0.23) | 1.00 (0.22) | 0.01 (−0.05 to 0.06); P=0.7 |
| Triglycerides† (mmol/l) | 1050 | 0.82 (0.39 to 1.72) | 0.83 (0.40 to 1.74) | 0.02 (−0.04 to 0.07); P=0.6 |
| Glucose homeostasis | ||||
| Glucose (mmol/l) | 1008 | 4.68 (0.58) | 4.72 (0.74) | 0.03 (−0.23 to 0.29); P=0.8 |
| Insulin† (mU/l) | 1008 | 15.36 (5.07 to 46.52) | 18.45 (6.37 to 53.41) | 0.18 (0.03 to 0.33); P=0.02 |
| HOMA score† | 1003 | 3.16 (1.00 to 10.00) | 3.79 (1.22 to 11.73) | 0.18 (0.04 to 0.32); P=0.015 |
HDL=high density lipoprotein; HOMA=homoeostasis modal assessment; LDL=low density lipoprotein.
*Based on linear regression models with robust standard errors.
†Values for intervention and control areas are geometric means and 95% reference ranges; mean differences are on log scale.