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. 2008 Jul 31;337:a769. doi: 10.1136/bmj.a769

Table 4.

 Estimated price differential between equally cost effective bivalent and quadrivalent human papillomavirus vaccines (vaccination of girls aged 12 years, 80% effective vaccine coverage, 100 year time horizon, and 3.5% discount rate for costs and benefits)

Age at vaccination and catch-up Duration of vaccine protection
10 years 20 years Life long
Girls aged 12 only:
 Median (£) 12.96 17.27 20.94
 95% centile (£) 22.06 26.59 30.30
 5% centile (£) 6.26 9.37 12.95
Girls aged 12 with catch-up to age 18:
 Median (£) 15.54 20.28 23.21
 95% centile (£) 25.26 29.91 32.79
 5% centile (£) 8.58 12.28 14.98

£1.00 (€1.26; $1.98).

Results are based on 50 000 meta-scenarios representing uncertainty in epidemiological and economic parameters.