Table 2. Clinical signs, virus replication and seroconversion in inoculated ferrets.
Virus | Inoculated ferrets | ||
Weight loss (%)a | Sneezing (Day of onset) | Serum (HI titer)b | |
RGWF10c | 1.8±0.57 | 0/3 | 1280, 1280, 1280 |
RGWF10 | 2.3d | 0/2 | 2560, 2560 |
Dk/HK/Y280/97 | 1.55±0.35 | 0/2 | 1280, 1280 |
RGQa88 | 2.8 d | 0/2 | 1280, 1280 |
Ck/HK/SF3/99 | 1.55±0.05 | 0/2 | 1280, 1280 |
Ck/Jordan/554/03 | 1.9±2.1 | 0/2 | 640, 640 |
RGMemphis98 | 6.54±0.13 | 2/2 (3, 3) | 5120, 2560 |
2WF10:6M98 | 5.1±0.85 | 2/2 (2, 2) | 2560, 2560 |
Average body weight loss±SD is shown.
Homologous virus was used in the HI assays to detect anti-H9 antibodies.
For the RGWF10 virus, two separate experiments were performed.
Only one ferret lost body weight.