Table III.

Comparison of protein and mRNA ratio measured by iTRAQ/Western blot and microarray/qPCR studies

Gene symbol	-Fold (MKR/WT) ± S.D.
	Protein ratio		mRNA ratio
	iTRAQ	Western blot	Microarray	qPCR
Pcx	0.43 ± 0.15	0.72 ± 0.08a	0.59 ± 0.08	0.70 ± 0.09a
Vamp2	0.59 ± 0.05	0.53 ± 0.06b	1.07 ± 0.07	1.12 ± 0.12
PDI/Erp59	2.43 ± 0.51	1.80 ± 0.19c	1.42 ± 0.17	1.34 ± 0.26a
Slc2a2/Glut2	0.42 ± 0.13	0.56 ± 0.03b	0.76 ± 0.00	0.61 ± 0.15c
Grp94	2.86 ± 0.89	3.10 ± 0.54c	1.56 ± 0.26	1.76 ± 0.27c
Bip/Grp78	2.25 ± 0.72	3.14 ± 0.72c	1.53 ± 0.27	1.55 ± 0.16b
Pc1	0.65 ± 0.20	0.53 ± 0.06b	1.20 ± 0.05	0.94 ± 0.16
Pc2	0.54 ± 0.14	0.72 ± 0.10a	0.92 ± 0.09	0.98 ± 0.31
Cpe	0.59 ± 0.08	0.68 ± 0.08c	1.10 ± 0.09	0.86 ± 0.16
Slc25a4/Ant1	0.63 ± 0.12	d	1.00 ± 0.07	1.01 ± 0.18
Sytl4	0.59 ± 0.18	d	0.61 ± 0.10	0.63 ± 0.02a
Maob	0.33 ± 0.07	d	0.71 ± 0.00	0.62 ± 0.06a

^ap < 0.05 compared with age-matched WT mice.

^bp < 0.001 compared with age-matched WT mice.

^cp < 0.01 compared with age-matched WT mice.

^dnot measured.