Table IV.

Unusual confirmed Csp6 substrate sites in various proteins

These sites were not predicted by combinatorial chemistry but were found to be specific for Csp6 in these proteins. FAK, focal adhesion kinase; TGEV, transmissible gastroenteritis coronavirus.

Caspase site	Protein substrate	Ref.
AQRD	Presenilin 1	31
DRHD	AP-2α	7
DSYD	Presenilin 2	31
DVVD	Caspase-6	18
ENDD	Presenilin 1	31
IVLD	Huntingtin	30
PEED	Topoisomerase I	5
SWKD	NS5A	71
TVAD	Periplakin	24
VSWD	FAK	23
VVPD	TGEV	72