Figure 2.

FFWY→A, FFW→A, and FW→A accumulate in dense lysosomes. (A) Schematic illustration of the point mutants within the cytoplasmic tail of the CD-MPR. Amino acids replacing the wild-type sequence are shown in bold letters. (B) Mouse L cells stably expressing FFWY→A, FFW→A, and FW→A were preincubated with pepstatin A and leupeptin for 24 h and then fractionated as described in Fig. 1.