Western blot analysis of NMS and IS used for passive immunization of C.B.-17 SCID mice. Lane 1, standard consisting of mouse mAbs to Hsp-70 (70 kDa), Hsp-60 (60 kDa), flagellin (41 kDa), OspB (34 kDa), OspA (31 kDa), OspC (24 kDa), pLA7 (20 kDa), and p7.5 (7.5 kDa). Lane 2, NMS, pooled from naive BALB/c mice. Lane 3, polyclonal IS generated in BALB/c mice immunized with rLip-OspA in ABM2 adjuvant. Lane 4, polyclonal IS generated in BALB/c mice immunized with rOspC in ABM2 adjuvant, as described in Materials and Methods.