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. 2007 Jan 16;13:31–38.

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This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Effects of stable expression of the β5 proteasome subunit on the viability of LECs after H₂O₂ treatment. Cell viability was measured by the MTT method 4 h after addition of H₂O₂. Treatment of LECs with H₂O₂ resulted in a dose-dependent decrease in viability in both β5 expressing cells and nonexpressing controls. Stable expression of β5 resulted in a significant protective effect against H₂O₂ toxicity in LECs. Similar results were obtained in the three independent cell lines analyzed.