Table 1.
Topical imiquimod in the treatment of dermatologic disorders
| Randomized clinical trials | Case reports |
|---|---|
| Genital and perianal warts | Extramammary Paget disease (Cohen et al 2006) |
| Actinic keratosis | Erythroplasia of Queyrat (Micali, Nasca et al 2003) |
| Basal cell carcinoma | Bowenoid papulosis (Goorney and Polorni 2004) |
| Bowen’s disease | Stucco keratosis (Stockfleth et al 2000) |
| Molluscum contagiosum | Porokeratosis of Mibelli (Jain 2006) |
| Leishmaniasis (plus antimonial agents) (Miranda-Verastegui et al 2005) | Invasive SSC (Martin-Garcia 2005) |
| Verrucous carcinoma (Schalock et al 2006) | |
| Metastatic melanoma (Wolf et al 2003) | |
| Non-randomized clinical trials | Cutaneous T-Cell lymphoma (Didona et al 2004) |
| Lentigo maligna (Naylor et al 2003) | Granuloma annulare (Badavanis et al 2005) |
| Vulvar intraepithelial neoplasia (Le et al 2006) | Infantile hemangioma (Hazen et al 2005) |
| Keloids (plus surgery) (Patel and Skinner 2006) | Genital herpes (Brummitt 2006) |
| Elastosis perforans serpiginosa (Kelly and Purcell 2006) | |
| Pyogenic granuloma (Goldenberg et al 2006) | |
| Case series | Langerhans cell hystiocytosis (Taverna et al 2006) |
| Morphea (Dytoc et al 2005) | Lymphomatoid papulosis (Hughes 2006) |
| Actinic cheilitis (Smith et al 2002) | Angiolymphoid hyperplasia (Redondo et al 2004) |
| Common warts ( Micali, Dall’Oglio et al 2003) | Orf (Erbagci, Erbagci et al 2005) |
| Mycosis fungoides (Deeths et al 2005) | Hyalohyphomycosis (Erbagci, Tuncel et al 2005) |
| Foreign body reaction (Baumann and Halem 2003) | |
| Trichilemmal carcinoma (Jo, Ko et al 2005) | |
| Eccrine poroma (Jo, Chin et al 2005) | |
| Lip papillomatosis (Rinne et al 2000) | |
| Keratoacanthoma (Di Lernia et al 2004) |