Table 2. Summary of the cleavage site motif in selected African H5 HPAI and LPAI viruses.
| Virus | Cleavage site | No. basic amino acids |
| Nigerian H5N2 HPAI | PQKEKRRKKR*GLF | 7 |
| PQREKRRKKR*GLF | ||
| African H5N1 HPAI 2006–2007a | PQGERRRKKR*GLF | 6 |
| A/chicken/Egypt/5610NAMRU3-F3/2006 (H5N1) | PQGKRRRKKR*GLF | 7 |
| A/chicken/Egypt/5611NAMRU3-AF/2006 (H5N1) | PQGKRRRKKR*GLF | 7 |
| A/Sudan/2006 (H5N1) HPAI | PQGEGRRKKR*GLF | 5 |
| A/ostrich/South Africa/N227/04 (H5N2) HPAI (9) | PQREKRRKKR*GLF | 7 |
| A/tern/South Africa/1961 (H5N3) HPAI | PQRETRRQKR*GLF | 5 |
| A/ostrich/South Africa/AI1091/2006 (HPAI) | PQRRKKR*GLF | 5 |
| A/ostrich/South Africa/AI1160/2006 (LPAI) | PQRETR*GLF | 2 |
| A/yellow-billed duck/South Africa/811/04 (H5N1LPAI) | PQRETR*GLF | 2 |
| A/mallard/Bavaria/1/2005 (H5N2 LPAI) | PQRETR*GLF | 2 |
Cleavage site motif of the HA sequence phylogenetically most closely related to the Nigerian H5N2 HA (A/mallard/Bavaria/1/2005) is included for comparison.
a
Representatives of all the sequenced African H5N1 HPAI viruses circulating in 2006–2007 (exceptions were observed in the Sudanese isolates and in 2 Egyptian isolates).