Figure 3.

MboI 3C analysis of the chicken α-globin gene domain in non-erythroid and transformed erythroid cells. (A) A MboI restriction map of the chicken α-globin gene domain and a scheme showing positions of functional elements of the domain. The short vertical lines above the scale show positions of MboI restriction sites. The other designations are as in Figure 2. (B and C) Relative frequencies of cross-linking between the anchor fragments bearing (B): α^D gene promoter, (C): α^A gene promoter and other fragments of the locus. The results of 3C analysis for induced HD3, cycling HD3 and DT40 cells are shown by the red, blue and green lines, respectively. The other notations are as in Figure 2.