Table II.
Summary statistics for the 48 sporozoite-induced and 61 trophozoite-induced charts, as in Table I, showing arithmetic means of the asexual-form and gametocyte densities (#/mm−3) and fevers (i.e., ≥101 F) between the first day of patency and the timing points given in Table I. The “mean CV” column gives the arithmetic mean of the coefficient of variation (standard deviation/mean) for each chart, which provides a measure of within-chart variation. Other conventions and abbreviations as in Table I.
| Sporozoite/trophozoite | Min | Max | Median | Mean | Std Dev | Mean CV |
|---|---|---|---|---|---|---|
| Mean number of asexuals per cubic millimeter, to | ||||||
| First asexual peak | 20.0/22.5 | 5,645.0/6,690.3 | 896.0/1,631.7 | 1,426.1/2,019.3 | 1,873.1/2,535.9 | 1.35/1.26 |
| Peak asexuals | 218.0/286.4 | 7,100.0/8,089.0 | 2,494.9/3,850.4 | 2,851.3/4,005.6 | 3,159.4/4,029.2 | 1.14/1.05 |
| First fever | 10.0/10.0 | 1,898.3/1,454.5 | 35.0/54.8 | 162.4/137.8 | 182.7/142.9 | 0.63/0.54 |
| Peak fever | 228.3/131.7 | 7,176.7/9,679.2 | 1,776.7/3,033.8 | 2,138.0/3,313.9 | 2,493.8/3,400.1 | 1.19/1.08 |
| Intervention (if both sexes rec) | 155.8/273.9 | 7,453.5/8,443.1 | 2,139.0/3,585.9 | 2,757.7/3,587.0 | 2,386.9/3,027.8 | 1.03/0.98 |
| First F gam | 255.1/551.3 | 4,575.0/7,487.8 | 2,020.0/2,890.1 | 2,146.4/3,138.7 | 2,483.9/3,235.9 | 1.17/1.10 |
| First M gam | 385.8/601.2 | 5,794.4/7,487.8 | 2,284.0/3,292.2 | 2,758.3/3,573.5 | 2,898.2/3,492.5 | 1.05/1.03 |
| Peak F gam | 385.8/898.2 | 7,310.6/8,165.2 | 3,396.7/3,809.9 | 3,389.4/4,162.5 | 3,008.4/3,408.4 | 0.91/0.85 |
| Peak M gam (if only M rec) | 385.8/680.7 | 7,310.6/8,401.0 | 3,136.8/3,877.3 | 3,305.1/4,139.7 | 2,969.5/3,336.9 | 0.91/0.84 |
| First gam | 623.1/483.7 | 6,387.5/6,672.7 | 2,761.2/2,003.9 | 2,965.5/2,183.6 | 3,004.4/2,355.7 | 1.07/1.27 |
| Peak gam | 682.1/787.3 | 6,720.9/9,350.0 | 3,746.4/4,319.0 | 3,923.9/4,641.6 | 3,066.2/3,727.0 | 0.79/0.89 |
| Gam (if both sexes) | ||||||
| Mean number of F per cubic millimeter to F peak | 10.0/10.0 | 213.5/210.0 | 69.0/47.0 | 70.6/52.7 | 37.0/30.6 | 0.47/0.52 |
| to intervention | 10.0/10.0 | 215.9/128.4 | 70.0/39.2 | 66.6/45.6 | 34.6/28.4 | 0.52/0.55 |
| Mean number of M per cubic millimeter to M peak | 10.0/10.0 | 102.9/292.7 | 28.0/24.5 | 35.7/34.3 | 20.3/21.2 | 0.46/0.54 |
| to intervention | 10.0/10.0 | 98.0/239.2 | 24.5/21.0 | 35.2/28.5 | 18.8/18.5 | 0.46/0.55 |
| Gam (if only M) | ||||||
| Mean number of gam per cubic millimeter to peak | 10.0/10.0 | 324.9/252.9 | 105.7/117.9 | 130.8/126.9 | 92.7/90.0 | 0.56/0.64 |
| to intervention | 10.0/10.0 | 409.0/303.4 | 122.9/112.4 | 134.1/118.9 | 90.9/83.1 | 0.55/0.63 |