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. 2008 Jun 1;10(3):154–160. doi: 10.1080/13651820801992567

Table I. Hilar cholangiocarcinoma: survival after palliative resection versus no resection.

Survival (months)
Study Evidence level Palliative resection (n) No resection (n) p
Pichlmayr et al., 1996 16 retrospective 2 b R1 resection (n=27) Median: 12.7 mo Exploratory laparotomy (n=99) 5.6 mo <0.0005
Kosuge et al., 1999 23 retrospective 2 b R1 resection (n=31) Non-resectional surgery (n=24) Non-surgical procedure (n=18) <0.0001 0.045
Jarnagin et al., 2001 25 retrospective 2 b R1 resection (n=18) Median: 21 mo Exploratory laparotomy (n=80) 16 mo NS
Kawasaki et al., 2003 15 retrospective 2 b R1 resection (n=25) Mean: 28 mo Exploratory laparotomy (n=27) 10 mo <0.0001
Hemming et al., 2005 18 prospective database 2 b R1 resection (n=11) Median: 24 mo Surgical bypass (n=14) 12 mo <0.05
Witzigmann et al., 2006 24 prospective database 2 b R1 resection (n=11) Median: 12.2 mo Stenting + PDT (n=68) 6.4 mo <0.05
R2 resection (n=7) Median 12.2 mo Stenting (n=56) 12 mo NS
Zhang et al., 2006 26 retrospective 2 b Palliative resection (n=61) Median: 10.2 mo Endoscopic biliary drainage (n=21) 6.2 mo NS

NS, not significant; PDT, photodynamic therapy