Table I. Hilar cholangiocarcinoma: survival after palliative resection versus no resection.
Survival (months) |
||||
---|---|---|---|---|
Study | Evidence level | Palliative resection (n) | No resection (n) | p |
Pichlmayr et al., 1996 16 retrospective | 2 b | R1 resection (n=27) Median: 12.7 mo | Exploratory laparotomy (n=99) 5.6 mo | <0.0005 |
Kosuge et al., 1999 23 retrospective | 2 b | R1 resection (n=31) | Non-resectional surgery (n=24) Non-surgical procedure (n=18) | <0.0001 0.045 |
Jarnagin et al., 2001 25 retrospective | 2 b | R1 resection (n=18) Median: 21 mo | Exploratory laparotomy (n=80) 16 mo | NS |
Kawasaki et al., 2003 15 retrospective | 2 b | R1 resection (n=25) Mean: 28 mo | Exploratory laparotomy (n=27) 10 mo | <0.0001 |
Hemming et al., 2005 18 prospective database | 2 b | R1 resection (n=11) Median: 24 mo | Surgical bypass (n=14) 12 mo | <0.05 |
Witzigmann et al., 2006 24 prospective database | 2 b | R1 resection (n=11) Median: 12.2 mo | Stenting + PDT (n=68) 6.4 mo | <0.05 |
R2 resection (n=7) Median 12.2 mo | Stenting (n=56) 12 mo | NS | ||
Zhang et al., 2006 26 retrospective | 2 b | Palliative resection (n=61) Median: 10.2 mo | Endoscopic biliary drainage (n=21) 6.2 mo | NS |
NS, not significant; PDT, photodynamic therapy