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Comparison of commonly used approaches for single-cell lysis.
| lysis mode | adherent cells | suspension cells | temporal resolution | protein denaturation | specialized equipment |
|---|---|---|---|---|---|
| laser | +++ | ++ | ns–μs | none/low | yes |
| electrical | ++ | +++ | >μs | none/low | yes |
| detergent | +++ | +++ | >s | low/high | no |
