TABLE 1.
Model | Animal ID | Injection site(s) | Cell type injected | Mean number of surviving ESCs per section (n = 5) |
---|---|---|---|---|
EPI | RS472 | RC, PLS | D3/bcl2 | 13 |
EPI | RS473a | RC, PLS | D3/bcl2 | 196b |
EPI | RS477a | RC, PLS | D3/bcl2 | 90b |
EPI | RS480a | RC, PLS | D3/EGFP | 199b |
EPI | RS481a | RC, PLS | D3/EGFP | 74b |
EPI | RS482a | RC, PLS | D3 | 15 |
EPI | RS485a | RC, PLS | D3/bcl2 | 213b |
EPI | RS486a | RC, PLS | D3/EGFP | 40 |
EPI | RS487 | RC, PLS | D3/EGFP | 26 |
EPI | RS488a | RC, PLS | D3 | 47 |
EPI | RS494 | RC, PLS | D3/bcl2 | 30 |
EPI | RS501 | RC, PLS | D3 | 65 |
EPI | RS440 | PLS | D3/EGFP | 0 |
EPI | RS468 | PLS | D3/EGFP | 12 |
EPI | RS474a | PLS | D3/bcl2 | 11 |
EPI | RS476a | PLS | D3/bcl2 | 63b |
EPI | RS478a | PLS | D3/bcl2 | 86 |
EPI | RS479a | PLS | D3/bcl2 | 10 |
EPI | RS484 | PLS | D3/bcl2 | 23 |
EPI | RS490 | PLS | D3 | 0 |
EPI | RS491 | PLS | D3 | 0 |
EPI | RS495 | PLS | D3/bcl2 | 56 |
EPI | RS499a | PLS | D3 | 63 |
LPI | RS454 | RC, PLS | D3/bcl2 | 7 |
LPI | RS456 | RC, PLS | D3/bcl2 | 3 |
LPI | RS457 | RC, PLS | D3/bcl2 | 3 |
LPI | RS469 | RC, PLS | D3/EGFP | 6 |
LPI | RS471a | RC, PLS | D3/bcl2 | 53 |
LPI | RS483 | RC, PLS | D3/EGFP | 0 |
LPI | RS493 | RC, PLS | D3/bcl2 | 0 |
LPI | RS437 | PLS | D3 | 11 |
LPI | RS441a | PLS | D3 | 3 |
LPI | RS442 | PLS | D3 | 0 |
LPI | RS455a | PLS | D3/bcl2 | 37 |
LPI | RS458 | PLS | D3/bcl2 | 1 |
LPI | RS465 | PLS | D3/EGFP | 0 |
LPI | RS470 | PLS | D3/bcl2 | 0 |
LPI | RS492 | PLS | D3/bcl2 | 9 |
Normal | RS489 | PLS | D3 | 6 |
Normal | RS496 | PLS | D3/bcl2 | 0 |
Normal | RS497 | PLS | D3/bcl2 | 0 |
Early post-injury (EPI) and late post-injury (LPI) gerbils received ESCs within 1–3 days and 1–4 weeks after ouabain treatment, respectively
ELS endolymphatic space, PLS perilymphatic space, RC, Rosenthal’s canal
aThese ears were processed for immunostaining for NF-200 and/or GFAP.
bThe vascular remodeling was present in surviving ESC masses.